1904 - "Grippe"

Die Kräutermischung beinhaltet neun verschiedene Inhaltsstoffe:

Petersilienblätter wirken entgiftend und gelten als Antioxidans, freie Radikale und oxidativer Stress werden neutralisiert. Petersilie enthält viele Mineralstoffe und Spurenelemente und 12 verschiedene Vitamine.

Holunderblüten wirken schweißtreibend bei Fieber und haben einen schleimlösenden Effekt bei Husten und Erkältung.

Königskerzenblüten: aufgrund des hohen Schleimstoffgehalt, wird die Königskerze traditionell als schleimlösendes Mittel bei entzündlichen Atemwegserkrankungen eingesetzt. Sie kann die Beschwerden einer Erkältung lindern.

Pfefferminzkraut lindert Erkältungskrankheiten, Bauchschmerzen sowie Kopfschmerzen und unterstützt die Wundheilung. Die spasmolytische Wirkung beruht auf der Interaktion zwischen den Kalziumkanälen in der Zellmembran der glatten Muskulatur und dem Menthol der Pfefferminze.

Wacholderbeerenextrakt wirkt entkrampfend auf die glatte Muskulatur, wie z. B: an den Wänden des Magen-Darm-Traktes, der Harnwege und der Blutgefäße. Das Extrakt besitzt u.a. eine harntreibende und schweißtreibende Wirkung.

Süßholzwurzelextrakt gilt als DAS „Kortison“ der Pflanzenheilkunde und ist fester Bestandteil der TCM. Es dient als auswurfförderndes Mittel bei Husten, vermindert die Magensäurebildung und besitzt antientzündliche Effekte. Auf Magen-Darm-Geschwüre und Gastritis hat es positive Effekte.  In Laborversuchen konnte nachgewiesen werden, dass Süßholzwurzel den Magenkeim Helicobacter pylori bekämpft.

Ascorbinsäure als Vitamin C Komponente.

Bockshornkleesamenextrakt hilft nachweislich gegen Appetitlosigkeit und äußerlich gegen lokale Hautentzündungen. In der Volksmedizin wird es bei entzündeten Atemwegen und zur Stärkung des Immunsystems angewendet.

Salbeiblattextrakt wird bei Entzündungen und Infektionen der Mund- und Rachenschleimhaut, zum Gurgeln bei Halsentzündungen und bei übermäßiger Schweißbildung angewendet. Die enthaltenen ätherischen Öle, Flavonoide und Gerbstoffe hemmen das Wachstum von Viren, Pilzen und Bakterien.

• Virale und bakterielle Infekte
• Grippaler Infekt
• Husten, Schnupfen, Heiserkeit
• Grippe, Sommergrippe
• Influenza mit Lungenentzündung, Fieber, Gliederschmerzen
• bei RS-Viren, Adeno-Vieren, Pneumonie
• Hals – Nasen-Ohren-Erkrankungen bzw. Entzündungen
• Gastroenteritis mit Übelkeit, Erbrechen, Durchfall
• Sekundär bei infekt-assoziierten Herzerkrankungen wie z.B. Myocarditis, Pericarditis, Herzrhythmusstörungen

Erfahrungswerte zeigen, dass Wolle Nr. 1904 gut alleine und als Akutmittel gegeben werden kann.

Ebenso kann es als Prophylaxe oder in einer Kombinationstherapie mit anderen Wolle Mischungen angewendet werden. Wolle Nr. 1904 kann bei allen Krankheitsbildern begleitend eingesetzt werden, wo Viren und Bakterien beteiligt sind.

Folgende Kombinationsmöglichkeiten haben sich bewährt:

• Nr. 1876 + Nr. 1904: Grippaler Infekt mit Husten bzw. Beteiligung der Bronchien
• Nr. 1892 + Nr. 1904: gemeinsam auch hochdosiert, in der akuten Phase, korrelieren gut und können gemeinsam auch „Festsitzendes“ in alten Bereichen eliminieren
• Nr. 1809 + Nr. 1904: viraler Infekt mit bakterieller Superinfektion
• Nr. 1854 + Nr. 1904: Herztherapie, Grippe, grippale Infekte v.a. bei Herzpatienten

Wichtige Begleit-Themen zu Wolle Nr. 1904 „Grippe“:

Bei allen grippalen Erkrankungen immer auf das Herz achten. Deshalb empfehlen wir eine Kombination mit Wolle Nr. 1854 „Herz“. Umgekehrt ist Wolle Nr. 1904 ein wichtiges Mittel in der Herztherapie.

• Petersilienblätter:
  • Äth. Öl (Apiol, Myristicin) -> bakteriostatisch,
  • Flavonoide -> antioxidativ, zellschützend,
  • Furanocumarine
• Holunderblüten:
  • diaphoretisches Wirkungsprinzip nicht aufgeklärt,
  • Flavonoidglykoside (Rutosid, Hyperosid, Astragalin, etc.) -> antiox.,
  • Pectin-Polysaccharide -> immunstimulierend
• Königskerzenblüten:
  • Saponine: expectorierend (über reflektorische Sekretion nach Reizung d. Magenschleimhaut)
  • Arabinogalactane (Schleimpolysaccharide): hustenreizlindernd
• Pfefferminzkraut:
  • Ätherisches Öl: Menthol -> Antibakteriell, antiviral, mucolytisch
• Wacholderbeerenextrakt: siehe Wolle 1892
• Süßholzwurzelextrakt:
  • Glycyrrhizinsäure: sekretolytisch-expectorierender Effekt
• Bockshornkleesamenextrakt:
  • Galactomannan-Schleimstoffe,
  • Steroidsaponine
  • Wirkprinzipien nicht aufgeklärt
• Salbeiblattextrakt:
  • Äth. Öl mit Thujon, Kampher, 1,8-Cineol: antiseptisch
  • Lamiaceengerbstoffe: antioxidative, Bei lokaler Anwendung (gurgeln) adstringierend
• Vitamin C:
  • Immunabwehrstärkend durch Stimulierung der Interferonproduktion (antiviral) und Erhöhung der Phagozytoseaktivität von Makrophagen

Empfohlene Dosierung: 3x täglich 2-3 Kapseln

Anwendungsempfehlung:

• prophylaktisch (1x täglich 1 Kps.)

oder

• im Krankheitsfall Anwendung wie hier beschrieben:
• Gleich zu Beginn der Grippe damit beginnen
• Über den Tag verteilt (1-1-1 Kps.) oder (2-1-2 Kps.), je nach Schwere der Infektion
• Essenziell zur Therapie ist eine reichliche Flüssigkeitszufuhr
• Alternativ können auch 1-2 Kapseln als Tee getrunken werden (hierfür den Kapselinhalt in heißes Wasser geben – den Bodensatz mittrinken.
  • In der Akutphase

• In Kombination mit Wolle Nr. 1892 in der Akutphase schnell hochdosieren. Empfohlenen Dosierung von Nr. 1892 hierbei: 2-2-2 oder 2-0-2 Kps. tägl.

• KI: Schwangerschaft, Überempfindlichkeit gegenüber einem Bestandteil, chronische Niereninsuffizienz
• UAW: Hautreaktionen, Blutdrucksteigerung, Nierenreizung
• WW: Cave Wirkungsverstärkung von Blutgerinnungshemmern möglich, Hypokaliämie bei glz. Einnahme von Schleifendiuretika, Wirkverstärkung Digitalisglykoside
• Schwangerschaft: nicht indiziert (abortive Eigenschaften von Petersilie und Wacholderbeere; Süßholzwurzel)

1. Paper: G A Linde et al.
   Genet Mol Res 2016
   Antifungal and antibacterial activities of Petroselinum crispum essential oil
   
   Abstract
   Parsley [Petroselinum crispum (Mill.) Fuss] is regarded as an aromatic, culinary, and medicinal plant and is used in the cosmetic, food, and pharmaceutical industries. However, few studies with conflicting results have been conducted on the antimicrobial activity of parsley essential oil. In addition, there have been no reports of essential oil obtained from parsley aerial parts, except seeds, as an alternative natural antimicrobial agent. Also, microorganism resistance is still a challenge for health and food production. Based on the demand for natural products to control microorganisms, and the re-evaluation of potential medicinal plants for controlling diseases, the objective of this study was to determine the chemical composition and antibacterial and antifungal activities of parsley essential oil against foodborne diseases and opportunistic pathogens. Seven bacteria and eight fungi were tested. The essential oil major compounds were apiol, myristicin, and b-phellandrene. Parsley essential oil had bacteriostatic activity against all tested bacteria, mainly Staphylococcus aureus, Listeria monocytogenes, and Salmonella enterica, at similar or lower concentrations than at least one of the controls, and bactericidal activity against all tested bacteria, mainly S. aureus, at similar or lower concentrations than at least one of the controls. This essential oil also had fungistatic activity against all tested fungi, mainly, Penicillium ochrochloron and Trichoderma viride, at lower concentrations than the ketoconazole control and fungicidal activity against all tested fungi at higher concentrations than the controls. Parsley is used in cooking and medicine, and its essential oil is an effective antimicrobial agent.
   https://pubmed.ncbi.nlm.nih.gov/27525894/
    
2. Review: Mohammad Hosein Farzaei et al.
   J Tradit Chin Med 2013
   Parsley: a review of ethnopharmacology, phytochemistry and biological activities
   
   Abstract
   Objective: To summarize comprehensive information concerning ethnomedicinal uses, phytochemistry, and pharmacological activities of parsley.
   Methods: Databases including PubMed, Scopus, Google Scholar, and Web of Science were searched for studies focusing on the ethnomedicinal use, phytochemical compounds and biological and pharmacological activities of parsley. Data were collected from 1966 to 2013. The search terms were: "Parsley" or "Petroselinum crispum" or "Petroselinum hortence".
   Results: Parsley has been used as carminative, gastro tonic, diuretic, antiseptic of urinary tract, anti-urolithiasis, anti-dote and anti-inflammatory and for the treatment of amenorrhea, dysmenorrhea, gastrointestinal disorder, hypertension, cardiac disease, urinary disease, otitis, sniffle, diabetes and also various dermal disease in traditional and folklore medicines. Phenolic compounds and flavonoids particularly apigenin, apiin and 6"-Acetylapiin; essential oil mainly myristicin and apiol; and also coumarins are the active compounds identified in Petroselinum crispum. Wide range of pharmacological activity including antioxidant, hepatoprotective, brain protective, anti-diabetic, analgesic, spasmolytic, immunosuppressant, anti-platelet, gastroprotective, cytoprotective, laxative, estrogenic, diuretic, hypotensive, antibacterial and antifungal activities have been exhibited for this plant in modern medicine
   Conclusion: It is expectant that this study resulted in improvement the tendencies toward Petroselinum crispum as a useful and important medicinal plant with wide range of proven medicinal activity
   https://pubmed.ncbi.nlm.nih.gov/24660617/
    
3. Paper: Maja Mikulic-Petkovsek et. al
   J Agric Food Chem 2015
   Traditional elderflower beverages: a rich source of phenolic compounds with high antioxidant activity
   
   Abstract
   Traditional elderflower beverages are very popular due to their pleasing taste and pro-health properties. Phenolics were quantified in three elderflower extracts (methanolic extraction and two water extracts prepared as fresh drinks according to local recipes) with HPLC-MS. Chromatographic patterns of methanolic and water extracts were quite similar; however, content levels of individual compounds differed between the two extraction solvents. Two feruloylquinic acids and two p-coumaroyl-caffeoylquinic acids and different flavonol glycosides have been identified in elderflowers for the first time. Hydroxycinnamic acids and flavonol glycosides were the major phenolic constituents in elderflowers. Methanolic extract contained higher levels of all phenolic groups compared to water-extracted samples. The yield of elderflower extracts depended on extract solution and time of extraction. Elderflower beverages were characterized by high total phenolic content (91.09 to 746.63 mg GAE/L). The results confirmed that elderflower beverages (sabesa, syrup) should be recommended as a good source of phenolics in human diet.
   https://pubmed.ncbi.nlm.nih.gov/25646848/
    
4. Paper: Giang Thanh Thi Ho et al.
   Int J Biol Macromol 2016
   RG-I regions from elderflower pectins substituted on GalA are strong immunomodulators
   
   Abstract
   Sambuci flos, also known as elderflower, has traditionally been used and is still in use for treatment of various types of illnesses related to the immune system such as cold, flu, fever and inflammation. Pectic polysaccharides from 50% EtOH, 50°C water and 100°C water extracts from elderflowers were treated with endo-α-d-(1-4)-polygalacturonase after previous de-esterification with the intention of isolating hairy regions and relate variation in structure to immunomodulating activity. High molecular weight sub-fractions (25-29kDa) and medium molecular weight sub-fractions (6-17kDa) were isolated after enzymatic treatment in addition to oligogalacturonides. Structural elucidation indicated that RG-I regions with AG-I and AG-II sidechains were the predominant structures in the high molecular weight sub-fractions, and two of three 1,4-linked GalA units in the rhamnogalacturonan backbone were branched in either position 2 or 3. The medium molecular weight sub-fractions had monomers and linkages typical for both RG-I and RG-II. The results showed that the high molecular RG-I containing polymers exhibit the highest dose-dependent complement fixing and macrophage stimulating activities.
   https://pubmed.ncbi.nlm.nih.gov/27475233/
    
5. Review: Arzu Ucar Turker et al.
   Phytother Res 2005
   Common mullein (Verbascum thapsus L.): recent advances in research
   
   Abstract
   Common mullein (Verbascum thapsus L.) is a medicinal plant readily found in roadsides, meadows and pasture lands and has been used to treat pulmonary problems, inflammatory diseases, asthma, spasmodic coughs, diarrhoea and migraine headaches. Although it has been used medicinally since ancient times, the popularity of common mullein has been increasing commercially for the past few years. Today, the dried leaves and flowers, swallow capsules, alcohol extracts and the flower oil of this plant can easily be found in health stores in the United States. The use of common mullein extracts in folk medicine begun recently to be supported by an increasing number of research studies. This paper thoroughly reviews all the scientific research related to Verbascum thapsus L. including plant tissue cultures and the biological properties of this plant.
   https://pubmed.ncbi.nlm.nih.gov/16222647/
    
6. Paper:
   Arzu Ucar Turker et al.
   J Ethnopharmacol 2002
   Biological activity of common mullein, a medicinal plan
   
   Abstract
   Common Mullein (Verbascum thapsus L., Scrophulariaceae) is a medicinal plant that has been used for the treatment of inflammatory diseases, asthma, spasmodic coughs, diarrhea and other pulmonary problems. The objective of this study was to assess the biological activity of Common Mullein extracts and commercial Mullein products using selected bench top bioassays, including antibacterial, antitumor, and two toxicity assays--brine shrimp and radish seed. Extracts were prepared in water, ethanol and methanol. Antibacterial activity (especially the water extract) was observed with Klebsiella pneumonia, Staphylococcus aureus, Staphylococcus epidermidis and Escherichia coli. Agrobacterium tumefaciens-induced tumors in potato disc tissue were inhibited by all extracts. Toxicity to Brine Shrimp and to radish seed germination and growth was observed at higher concentrations of the extracts.
   https://pubmed.ncbi.nlm.nih.gov/12241986/
    
7. Review: Yu-Jin Kwon et al
   J Med Food 2020
   A Review of the Pharmacological Efficacy and Safety of Licorice Root from Corroborative Clinical Trial Finding
   
   Abstract
   Since ancient times, licorice, the root of Glycyrrhiza glabra, has been known to have a wide spectrum of therapeutic effects. Glycyrrhizin is cleaved to glycyrrhizic acid, which is subsequently converted to glycyrrhetic acid by human intestinal microflora. Glycyrrhetic acid is a potent inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD) and performs a range of corticosteroid-like activities. The pharmacologic effects of licorice contribute to its anti-inflammatory, antioxidative, anti-allergenic, and antimicrobial properties. Licorice has been used to treat liver disease, gastrointestinal disorders, oral disease, and various skin disorders and has been used in gum, candy, herbs, alcoholic beverages, and food supplements. Licorice and its extracts, especially glycyrrhizin, can be taken orally, through the skin (in the form of gels and oils), and intravenously. Licorice demonstrates mineralocorticoid-like activity not only by inhibiting 11β-HSD2, but also by binding to a mineralocorticoid receptor, leading to potentially adverse risks of mineralocorticoid-like overactivity. Chronic use of licorice can lead to hypokalemia and hypertension, and some people are more sensitive to licorice exposure. Based on clinical trials, this review summarizes the positive effects of licorice and other reported side effects
   https://pubmed.ncbi.nlm.nih.gov/31874059/
    
8. Review: Kalyan C Nagulapalli Venkata et al.
   Mol Nutr Food Res 2017
   A small plant with big benefits: Fenugreek (Trigonella foenum-graecum Linn.) for disease prevention and health promotion
   
   Abstract
   Plant-derived natural products have long-standin